4f7i: Difference between revisions

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[[Image:4f7i.jpg|left|200px]]


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==Structure of Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH==
The line below this paragraph, containing "STRUCTURE_4f7i", creates the "Structure Box" on the page.
<StructureSection load='4f7i' size='340' side='right'caption='[[4f7i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4f7i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F7I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F7I FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPM:3-ISOPROPYLMALIC+ACID'>IPM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MPO:3[N-MORPHOLINO]PROPANE+SULFONIC+ACID'>MPO</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
{{STRUCTURE_4f7i|  PDB=4f7i  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f7i OCA], [https://pdbe.org/4f7i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f7i RCSB], [https://www.ebi.ac.uk/pdbsum/4f7i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f7i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEU3_THET8 LEU3_THET8] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]


===Structure of Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH===
==See Also==
 
*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4f7i]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F7I OCA].
[[Category: Large Structures]]
[[Category: 3-isopropylmalate dehydrogenase]]
[[Category: Thermus thermophilus HB8]]
[[Category: Thermus thermophilus]]
[[Category: Graczer E]]
[[Category: Graczer, E.]]
[[Category: Pallo A]]
[[Category: Pallo, A.]]
[[Category: Vas M]]
[[Category: Vas, M.]]
[[Category: Weiss MS]]
[[Category: Weiss, M S.]]
[[Category: Zavodszky P]]
[[Category: Zavodszky, P.]]
[[Category: 3-ipm-dh]]
[[Category: Beta-ipm dehydrogenase]]
[[Category: Imdh]]
[[Category: Ipmdh]]
[[Category: Isopropylmalate dehydrogenase]]
[[Category: Oxidoreductase]]
Retrieved from "https://proteopedia.org/4f7i"