2ats: Difference between revisions

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[[Image:2ats.png|left|200px]]


<!--
==Dihydrodipicolinate synthase co-crystallised with (S)-lysine==
The line below this paragraph, containing "STRUCTURE_2ats", creates the "Structure Box" on the page.
<StructureSection load='2ats' size='340' side='right'caption='[[2ats]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ats]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ATS FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
{{STRUCTURE_2ats|  PDB=2ats  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ats FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ats OCA], [https://pdbe.org/2ats PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ats RCSB], [https://www.ebi.ac.uk/pdbsum/2ats PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ats ProSAT]</span></td></tr>
 
</table>
===Dihydrodipicolinate synthase co-crystallised with (S)-lysine===
== Function ==
 
[https://www.uniprot.org/uniprot/DAPA_ECOLI DAPA_ECOLI] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<ref>PMID:20503968</ref> <ref>PMID:8993314</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[2ats]] is a 2 chain structure of [[Dihydrodipicolinate synthase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATS OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/2ats_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ats ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
[[Category: Dihydrodipicolinate synthase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Devenish, S R.A.]]
[[Category: Large Structures]]
[[Category: Dobson, R C.J.]]
[[Category: Devenish SRA]]
[[Category: Gerrard, J A.]]
[[Category: Dobson RCJ]]
[[Category: Jameson, G B.]]
[[Category: Gerrard JA]]
[[Category: Dhdp]]
[[Category: Jameson GB]]
[[Category: Dihydrodipicolinate synthase]]
[[Category: Inhibition]]
[[Category: Lyase]]
[[Category: Lysine]]

Latest revision as of 13:41, 13 March 2024

Dihydrodipicolinate synthase co-crystallised with (S)-lysine

2ats, resolution 1.90Å

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