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[[Image:3sdf.png|left|200px]]


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==Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Lipoteichoic acid at 2.1 A Resolution==
The line below this paragraph, containing "STRUCTURE_3sdf", creates the "Structure Box" on the page.
<StructureSection load='3sdf' size='340' side='right'caption='[[3sdf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3sdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SDF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=LTC:(2S)-1-({3-O-[2-(ACETYLAMINO)-4-AMINO-2,4,6-TRIDEOXY-BETA-D-GALACTOPYRANOSYL]-ALPHA-D-GLUCOPYRANOSYL}OXY)-3-(HEPTANOYLOXY)PROPAN-2-YL+(7Z)-PENTADEC-7-ENOATE'>LTC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3sdf|  PDB=3sdf  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sdf OCA], [https://pdbe.org/3sdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sdf RCSB], [https://www.ebi.ac.uk/pdbsum/3sdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sdf ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Lipoteichoic acid at 2.1 A Resolution===
== Function ==
 
[https://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>  Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>  Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>  The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>
 
==About this Structure==
[[3sdf]] is a 1 chain structure of [[Lactoferrin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SDF OCA].  


==See Also==
==See Also==
*[[Lactoferrin|Lactoferrin]]
*[[Lactoferrin|Lactoferrin]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Bhushan, A.]]
[[Category: Large Structures]]
[[Category: Gautam, L.]]
[[Category: Bhushan A]]
[[Category: Kaur, P.]]
[[Category: Gautam L]]
[[Category: Sharma, S.]]
[[Category: Kaur P]]
[[Category: Shukla, P K.]]
[[Category: Sharma S]]
[[Category: Singh, T P.]]
[[Category: Shukla PK]]
[[Category: Sinha, M.]]
[[Category: Singh TP]]
[[Category: C-lobe]]
[[Category: Sinha M]]
[[Category: Complex]]
[[Category: Hydrolase]]
[[Category: Iron binding]]
[[Category: Lipoteichoic acid]]
Retrieved from "https://proteopedia.org/3sdf"