2lui: Difference between revisions
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New page: '''Unreleased structure''' The entry 2lui is ON HOLD Authors: Erlendsson, S., Teilum, K. Description: Chemical Shift Assignments for the PICK1 PDZ domain fused to the C10 DAT ligand |
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==Structure of the PICK PDZ domain in complex with the DAT C-terminal== | |||
<StructureSection load='2lui' size='340' side='right'caption='[[2lui]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2lui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LUI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lui OCA], [https://pdbe.org/2lui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lui RCSB], [https://www.ebi.ac.uk/pdbsum/2lui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lui ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Erlendsson S]] | |||
[[Category: Gether U]] | |||
[[Category: Heidarsson PO]] | |||
[[Category: Madsen KL]] | |||
[[Category: Poulsen FM]] | |||
[[Category: Rathje M]] | |||
[[Category: Teilum K]] | |||
Latest revision as of 06:57, 1 May 2024
Structure of the PICK PDZ domain in complex with the DAT C-terminal
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