3scz: Difference between revisions
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==Combining crystallographic, thermodynamic, and molecular dynamics studies of Mycobacterium tuberculosis purine nucleoside phosphorylase== | |||
<StructureSection load='3scz' size='340' side='right'caption='[[3scz]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3scz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SCZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3scz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3scz OCA], [https://pdbe.org/3scz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3scz RCSB], [https://www.ebi.ac.uk/pdbsum/3scz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3scz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PUNA_MYCTU PUNA_MYCTU] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine (By similarity). | |||
=== | ==See Also== | ||
*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Basso LA]] | |||
[[Category: Caceres RA]] | |||
[[Category: Basso | [[Category: Ducati RG]] | ||
[[Category: Caceres | [[Category: Rosado LA]] | ||
[[Category: Ducati | [[Category: Santos DS]] | ||
[[Category: Rosado | [[Category: Timmers LFSM]] | ||
[[Category: Santos | [[Category: De Azevedo Jr WF]] | ||
[[Category: Timmers | |||
[[Category: | |||
Latest revision as of 09:49, 1 March 2024
Combining crystallographic, thermodynamic, and molecular dynamics studies of Mycobacterium tuberculosis purine nucleoside phosphorylase
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