3v8q: Difference between revisions

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[[Image:3v8q.png|left|200px]]


{{STRUCTURE_3v8q| PDB=3v8q | SCENE= }}
==Crystal structure of NAD kinase 1 H223E mutant from Listeria monocytogenes in complex with 5'-amino-5'-deoxyadenosine==
<StructureSection load='3v8q' size='340' side='right'caption='[[3v8q]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3v8q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V8Q FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5N5:5-AMINO-5-DEOXYADENOSINE'>5N5</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v8q OCA], [https://pdbe.org/3v8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v8q RCSB], [https://www.ebi.ac.uk/pdbsum/3v8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v8q ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NADK1_LISMO NADK1_LISMO] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.[HAMAP-Rule:MF_00361]<ref>PMID:17686780</ref> <ref>PMID:22608967</ref>


===Crystal structure of NAD kinase 1 H223E mutant from Listeria monocytogenes in complex with 5'-amino-5'-deoxyadenosine===
==See Also==
 
*[[NAD kinase|NAD kinase]]
{{ABSTRACT_PUBMED_22608967}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[3v8q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8Q OCA].
</StructureSection>
 
[[Category: Large Structures]]
==Reference==
<ref group="xtra">PMID:022608967</ref><references group="xtra"/>
[[Category: Listeria monocytogenes]]
[[Category: Listeria monocytogenes]]
[[Category: Assairi, L.]]
[[Category: Assairi L]]
[[Category: Dugu, L.]]
[[Category: Dugu L]]
[[Category: Dussurget, O.]]
[[Category: Dussurget O]]
[[Category: Gelin, M.]]
[[Category: Gelin M]]
[[Category: Huteau, V.]]
[[Category: Huteau V]]
[[Category: Labesse, G.]]
[[Category: Labesse G]]
[[Category: Morellato, L.]]
[[Category: Morellato L]]
[[Category: Pochet, S.]]
[[Category: Pochet S]]
[[Category: Poncet-Montange, G.]]
[[Category: Poncet-Montange G]]
[[Category: Inorganic polyphosphate/atp-nad kinase 1]]
[[Category: Ligand-screening by crystallography]]
[[Category: Transferase]]
[[Category: Two-domain kinase]]

Latest revision as of 10:33, 1 March 2024

Crystal structure of NAD kinase 1 H223E mutant from Listeria monocytogenes in complex with 5'-amino-5'-deoxyadenosine

3v8q, resolution 2.37Å

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