Variable lymphocyte receptor: Difference between revisions

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{{STRUCTURE_2o6q|  PDB=2o6q  | SIZE=400| SCENE= |right|  CAPTION=Inshore hagfish variable lymphocyte receptor leucin-rich repeat, [[2o6q]] }}
<StructureSection load='' size='350' side='right' scene='45/456531/Cv/1' caption='Variable lymphocyte receptor of lamprey (grey) bound to a protein antigen (green) ([[3g3a]]), resolution 2.20&Aring;'>
'''Variable lymphocyte receptors''' (VLRs) are [[leucine-rich repeat]] (LRR) family proteins that mediate adaptive immune responses in the jawless vertebrates, lampreys and hagfish. <ref>PMID: 17192264</ref>
'''Variable lymphocyte receptors''' (VLRs) are [[leucine-rich repeat]] (LRR) family proteins that mediate adaptive immune responses in the jawless vertebrates, lampreys and hagfish. <ref>PMID: 17192264</ref>
[[Image:3g3a biol unitsurf.png|370px|right|thumb| [[Lamprey Variable Lymphocyte Receptor]] in complex with a protein antigen ([[3g3a]])]]


{{STRUCTURE_3g3a|  PDB=3g3a  |  SCENE=Variable_Lymphocyte_Receptors/3g3a_biological_unit/3 |CAPTION= Variable lymphocyte receptor of lamprey bound to a protein antigen ([[3g3a]]), resolution 2.20&Aring;}}
<scene name='45/456531/Cv/3'>Leucines highlighted in magenta</scene>.


[[Image:3g3a biol unitsurf.png|370px|left|thumb| [[Lamprey Variable Lymphocyte Receptor]] in complex with a protein antigen ([[3g3a]])]]
{{Clear}}


Articles in Proteopedia concerning Variable lymphocyte receptors include:
==See Also==
*[[Lamprey Variable Lymphocyte Receptor]]
*[[Lamprey Variable Lymphocyte Receptor]]
==References==
<references/>
==See Also==
*[[leucine-rich repeat|Leucine-rich Repeat Proteins]]
*[[leucine-rich repeat|Leucine-rich Repeat Proteins]]
*[[Antibody]]
*[[Antibody]]
*[[Forkhead box protein]]
*[[Forkhead box protein]]
==3D structures of variable lymphocyte receptor==
[[Variable lymphocyte receptor 3D structures]]
</StructureSection>
Articles in Proteopedia concerning Variable lymphocyte receptors include:
*[[Lamprey Variable Lymphocyte Receptor]]


==Additional Literature==
==Additional Literature==
<ref group="xtra">PMID: 21293377</ref><ref group="xtra">PMID: 20660361</ref><ref group="xtra">PMID: 20482318</ref><ref group="xtra">PMID: 19543291</ref><ref group="xtra">PMID: 20660361</ref> <ref group="xtra">PMID: 18238899 </ref><ref group="xtra">PMID: 18818359 </ref><references group="xtra"/>See [[Lamprey Variable Lymphocyte Receptor]] for details.
<ref group="xtra">PMID: 21293377</ref><ref group="xtra">PMID: 20660361</ref><ref group="xtra">PMID: 20482318</ref><ref group="xtra">PMID: 19543291</ref><ref group="xtra">PMID: 20660361</ref> <ref group="xtra">PMID: 18238899 </ref><ref group="xtra">PMID: 18818359 </ref><references group="xtra"/>See [[Lamprey Variable Lymphocyte Receptor]] for details.
 
==References==
{{TOC limit|limit=2}}
<references/>
 
==3D structures of variable lymphocyte receptor==
 
''Updated December 2011''
 
[[3m19]], [[3g39]], [[2r9u]] - mlVLR ectodomain – marine lamprey<br />
[[3m18]], [[3g3a]] – mlVLR ectodomain + lysozyme<br />
[[3g3b]] - mlVLR ectodomain (mutant) + lysozyme<br />
[[3e6j]] - mlVLR ectodomain + trisaccharide<br />
[[2o6q]], [[2o6r]], [[2o6s]] – IhVLR leucine-rich repeat – inshore hagfish<br />
[[2z62]], [[2z63]], [[2z66]] – IhVLR/hTLR4<br />
[[2z80]], [[2z81]], [[2z82]], [[3a78]], [[3a7c]] – IhVLR/hTLR2<br />
[[2z65]] – IhVLR/hTLR4 + lymphocyte antigen 96<br />
[[2z7x]] – IhVLR/hTLR1 + IhVLR/hTLR2 + tri-acylated lipopeptide<br />
[[3a79]] - IhVLR/hTLR2 + IhVLR/hTLR6 + tri-acylated lipopeptide
 
   [[Category:Topic Page]]
   [[Category:Topic Page]]
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