3tll: Difference between revisions

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[[Image:3tll.jpg|left|200px]]


{{STRUCTURE_3tll| PDB=3tll | SCENE= }}
==tRNA-Guanine Transglycosylase in complex with N-Ethyl-lin-benzoguanine Inhibitor==
<StructureSection load='3tll' size='340' side='right'caption='[[3tll]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tll]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=62D:6-(ETHYLAMINO)-2-(METHYLAMINO)-3,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE'>62D</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tll OCA], [https://pdbe.org/3tll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tll RCSB], [https://www.ebi.ac.uk/pdbsum/3tll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tll ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]


===tRNA-Guanine Transglycosylase in complex with N-Ethyl-lin-benzoguanine Inhibitor===
==See Also==
 
*[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]]
{{ABSTRACT_PUBMED_22736391}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[3tll]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLL OCA].
 
==Reference==
<ref group="xtra">PMID:022736391</ref><references group="xtra"/>
[[Category: Zymomonas mobilis]]
[[Category: Zymomonas mobilis]]
[[Category: TRNA-guanine transglycosylase]]
[[Category: Heine A]]
[[Category: Heine, A.]]
[[Category: Immekus F]]
[[Category: Immekus, F.]]
[[Category: Klebe G]]
[[Category: Klebe, G.]]
[[Category: Biosynthesis]]
[[Category: Glycosyltransferase]]
[[Category: Metal-binding]]
[[Category: Queuosine]]
[[Category: Tim barrel]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Trna processing]]
Retrieved from "https://proteopedia.org/3tll"