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[[Image:4fbw.png|left|200px]]


{{STRUCTURE_4fbw|  PDB=4fbw  |  SCENE=  }}
==Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site==
 
<StructureSection load='4fbw' size='340' side='right'caption='[[4fbw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4fbw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FBW FirstGlance]. <br>
{{ABSTRACT_PUBMED_22705791}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fbw OCA], [https://pdbe.org/4fbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fbw RCSB], [https://www.ebi.ac.uk/pdbsum/4fbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fbw ProSAT]</span></td></tr>
[[4fbw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FBW OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/RAD32_SCHPO RAD32_SCHPO] Required for the repair of double strand breaks (DSB) caused by gamma and UV radiation. May work in conjunction with rhp51.
<ref group="xtra">PMID:022705791</ref><references group="xtra"/>
__TOC__
[[Category: Schizosaccharomyces pombe]]
</StructureSection>
[[Category: Hopfner, K P.]]
[[Category: Large Structures]]
[[Category: Lammens, K.]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Schiller, C B.]]
[[Category: Hopfner KP]]
[[Category: Dna double-strand break repair]]
[[Category: Lammens K]]
[[Category: Hydrolase]]
[[Category: Schiller CB]]
[[Category: Hydrolase-protein binding complex]]
[[Category: Nuclease]]

Latest revision as of 11:13, 1 March 2024

Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site

4fbw, resolution 2.20Å

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