3vd0: Difference between revisions

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[[Image:3vd0.png|left|200px]]


{{STRUCTURE_3vd0| PDB=3vd0 | SCENE= }}
==structure of p73 DNA binding domain tetramer modulates p73 transactivation==
<StructureSection load='3vd0' size='340' side='right'caption='[[3vd0]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3vd0]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VD0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vd0 OCA], [https://pdbe.org/3vd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vd0 RCSB], [https://www.ebi.ac.uk/pdbsum/3vd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vd0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>


===structure of p73 DNA binding domain tetramer modulates p73 transactivation===
==See Also==
 
*[[P73|P73]]
{{ABSTRACT_PUBMED_22474346}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[3vd0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VD0 OCA].
</StructureSection>
 
==Reference==
<ref group="xtra">PMID:022474346</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ethayathulla, A S]]
[[Category: Large Structures]]
[[Category: Nguyen, S.]]
[[Category: Ethayathulla AS]]
[[Category: Tse, P W.]]
[[Category: Nguyen S]]
[[Category: Viadiu, H.]]
[[Category: Tse PW]]
[[Category: Antitumor protein-dna complex]]
[[Category: Viadiu H]]
[[Category: Beta-immunoglobulin-like fold]]
[[Category: Dna]]
[[Category: Protein dna complex]]
[[Category: Tumour suppressor]]
Retrieved from "https://proteopedia.org/3vd0"