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[[Image:4fgz.jpg|left|200px]]


{{STRUCTURE_4fgz|  PDB=4fgz  |  SCENE=  }}
==Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine==
 
<StructureSection load='4fgz' size='340' side='right'caption='[[4fgz]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
===Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4fgz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FGZ FirstGlance]. <br>
{{ABSTRACT_PUBMED_22771008}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.994&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CQA:4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL'>CQA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fgz OCA], [https://pdbe.org/4fgz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fgz RCSB], [https://www.ebi.ac.uk/pdbsum/4fgz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fgz ProSAT]</span></td></tr>
[[4fgz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FGZ OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/Q6T755_PLAFA Q6T755_PLAFA]
<ref group="xtra">PMID:022771008</ref><references group="xtra"/>
__TOC__
[[Category: Phosphoethanolamine N-methyltransferase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Alpert, T D.]]
[[Category: Alpert TD]]
[[Category: Jez, J M.]]
[[Category: Jez JM]]
[[Category: Lee, S G.]]
[[Category: Lee SG]]
[[Category: Methylation]]
[[Category: Sam binding]]
[[Category: Sam-dependent methyltransferase]]
[[Category: Transferase]]

Latest revision as of 11:16, 1 March 2024

Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine

4fgz, resolution 1.99Å

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