3u57: Difference between revisions

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[[Image:3u57.png|left|200px]]


{{STRUCTURE_3u57|  PDB=3u57  |  SCENE=  }}
==Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity==
 
<StructureSection load='3u57' size='340' side='right'caption='[[3u57]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
===Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3u57]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U57 FirstGlance]. <br>
{{ABSTRACT_PUBMED_22004291}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DH8:(2BETA,7BETA,16S,17R,19E,21BETA)-21-(BETA-D-GLUCOPYRANOSYLOXY)-2,7-DIHYDRO-7,17-CYCLOSARPAGAN-17-YL+ACETATE'>DH8</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u57 OCA], [https://pdbe.org/3u57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u57 RCSB], [https://www.ebi.ac.uk/pdbsum/3u57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u57 ProSAT]</span></td></tr>
[[3u57]] is a 2 chain structure of [[Beta-glucosidase]] with sequence from [http://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U57 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RG1_RAUSE RG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the treatment of heart disorders.<ref>PMID:10975500</ref>


==See Also==
==See Also==
*[[Beta-glucosidase|Beta-glucosidase]]
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:022004291</ref><references group="xtra"/>
__TOC__
[[Category: Raucaffricine beta-glucosidase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Rauvolfia serpentina]]
[[Category: Rauvolfia serpentina]]
[[Category: Barleben, L.]]
[[Category: Barleben L]]
[[Category: Lin, H.]]
[[Category: Lin H]]
[[Category: Panjikar, S.]]
[[Category: Panjikar S]]
[[Category: Rajendran, C.]]
[[Category: Rajendran C]]
[[Category: Ruppert, M.]]
[[Category: Ruppert M]]
[[Category: Stoeckigt, J.]]
[[Category: Stoeckigt J]]
[[Category: Wang, M.]]
[[Category: Wang M]]
[[Category: Xia, L.]]
[[Category: Xia L]]
[[Category: Alkaloid glucosidase]]
[[Category: Hydrolase]]
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