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[[Image:3al0.png|left|200px]]


{{STRUCTURE_3al0|  PDB=3al0  |  SCENE=  }}
==Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state.==
 
<StructureSection load='3al0' size='340' side='right'caption='[[3al0]], [[Resolution|resolution]] 3.37&Aring;' scene=''>
===Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3al0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AL0 FirstGlance]. <br>
{{ABSTRACT_PUBMED_20882017}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.368&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSU:O5-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE'>GSU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3al0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3al0 OCA], [https://pdbe.org/3al0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3al0 RCSB], [https://www.ebi.ac.uk/pdbsum/3al0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3al0 ProSAT]</span></td></tr>
[[3al0]] is a 4 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [http://en.wikipedia.org/wiki/Thermotoga_maritima,_synthetic Thermotoga maritima, synthetic]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AL0 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/GATA_THEMA GATA_THEMA] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/3al0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3al0 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
*[[Glutamyl-tRNA(Gln) amidotransferase|Glutamyl-tRNA(Gln) amidotransferase]]
==Reference==
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
<ref group="xtra">PMID:020882017</ref><references group="xtra"/>
__TOC__
[[Category: Thermotoga maritima]]
</StructureSection>
[[Category: Thermotoga maritima, synthetic]]
[[Category: Large Structures]]
[[Category: Ito, T.]]
[[Category: Synthetic construct]]
[[Category: Yokoyama, S.]]
[[Category: Thermotoga maritima MSB8]]
[[Category: Ligase-rna complex]]
[[Category: Ito T]]
[[Category: Protein-rna complex]]
[[Category: Yokoyama S]]
Retrieved from "https://proteopedia.org/3al0"