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[[Image:3f9r.png|left|200px]]


{{STRUCTURE_3f9r|  PDB=3f9r  |  SCENE=  }}
==Crystal Structure of Trypanosoma Brucei phosphomannosemutase, TB.10.700.370==
 
<StructureSection load='3f9r' size='340' side='right'caption='[[3f9r]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
===Crystal Structure of Trypanosoma Brucei phosphomannosemutase, TB.10.700.370===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3f9r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F9R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F9R FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[3f9r]] is a 2 chain structure of [[Phosphomannomutase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F9R OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f9r OCA], [https://pdbe.org/3f9r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f9r RCSB], [https://www.ebi.ac.uk/pdbsum/3f9r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f9r ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q38AW2_TRYB2 Q38AW2_TRYB2] Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.[RuleBase:RU361118]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f9/3f9r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f9r ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphomannomutase|Phosphomannomutase]]
*[[Phosphomannomutase|Phosphomannomutase]]
[[Category: Phosphomannomutase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
[[Category: Ali, A.]]
[[Category: Ali A]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bandini, G.]]
[[Category: Bandini G]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Bountra, C.]]
[[Category: Bountra C]]
[[Category: Cossar, D.]]
[[Category: Cossar D]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Ferguson, M A.J.]]
[[Category: Ferguson MAJ]]
[[Category: Guther, L.]]
[[Category: Guther L]]
[[Category: Hui, R.]]
[[Category: Hui R]]
[[Category: Kozieradzki, I.]]
[[Category: Kozieradzki I]]
[[Category: Lam, A.]]
[[Category: Lam A]]
[[Category: Lin, Y H.]]
[[Category: Lin YH]]
[[Category: MacKenzie, F.]]
[[Category: MacKenzie F]]
[[Category: Qiu, W.]]
[[Category: Qiu W]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Schapira M]]
[[Category: Schapira, M.]]
[[Category: Shamshad A]]
[[Category: Shamshad, A.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Wernimont AK]]
[[Category: Wernimont, A K.]]
[[Category: Zhao Y]]
[[Category: Zhao, Y.]]
[[Category: Isomerase]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Trypanosome glycobiology structural genomic]]