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[[Image:1e3b.png|left|200px]]


{{STRUCTURE_1e3b|  PDB=1e3b  |  SCENE=  }}
==CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3==
 
<StructureSection load='1e3b' size='340' side='right'caption='[[1e3b]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
===CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1e3b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E3B FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3EP:TRIETHYLPHOSPHANE'>3EP</scene>, <scene name='pdbligand=AU:GOLD+ION'>AU</scene></td></tr>
[[1e3b]] is a 1 chain structure of [[Cyclophilin]] with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E3B OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e3b OCA], [https://pdbe.org/1e3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e3b RCSB], [https://www.ebi.ac.uk/pdbsum/1e3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e3b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CYP3_CAEEL CYP3_CAEEL] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/1e3b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e3b ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cyclophilin|Cyclophilin]]
*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:011028014</ref><references group="xtra"/>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Dornan, J.]]
[[Category: Large Structures]]
[[Category: Robinson, S P.]]
[[Category: Dornan J]]
[[Category: Sadler, P J.]]
[[Category: Robinson SP]]
[[Category: Taylor, P.]]
[[Category: Sadler PJ]]
[[Category: Walkinshaw, M D.]]
[[Category: Taylor P]]
[[Category: Zou, J.]]
[[Category: Walkinshaw MD]]
[[Category: Aupet3 adduct cyclophilin antiarthritic gold]]
[[Category: Zou J]]
[[Category: Isomerase]]
Retrieved from "https://proteopedia.org/1e3b"