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[[Image:2qkf.png|left|200px]]


{{STRUCTURE_2qkf|  PDB=2qkf  |  SCENE=  }}
==Crystal structure of 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis==
 
<StructureSection load='2qkf' size='340' side='right'caption='[[2qkf]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
===Crystal structure of 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2qkf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_B Neisseria meningitidis serogroup B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QKF FirstGlance]. <br>
{{ABSTRACT_PUBMED_16267580}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkf OCA], [https://pdbe.org/2qkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkf RCSB], [https://www.ebi.ac.uk/pdbsum/2qkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkf ProSAT]</span></td></tr>
[[2qkf]] is a 4 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKF OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/KDSA_NEIMB KDSA_NEIMB]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qkf ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aldolase|Aldolase]]
*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016267580</ref><ref group="xtra">PMID:019447118</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: 3-deoxy-8-phosphooctulonate synthase]]
[[Category: Neisseria meningitidis serogroup B]]
[[Category: Neisseria meningitidis serogroup b]]
[[Category: Cochrane FC]]
[[Category: Cochrane, F C.]]
[[Category: Jameson GB]]
[[Category: Jameson, G B.]]
[[Category: Parker EJ]]
[[Category: Parker, E J.]]
[[Category: Patchett ML]]
[[Category: Patchett, M L.]]
[[Category: Kdo8 kdop]]
[[Category: Kdo8p]]
[[Category: Kdop]]
[[Category: Lipopolysaccharide]]
[[Category: Lipopolysaccharide biosynthesis]]
[[Category: Lyase]]
[[Category: Manno-octulosonate]]
[[Category: Synthase]]
[[Category: Tim barrel]]
[[Category: Transferase]]