3hzn: Difference between revisions

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[[Image:3hzn.png|left|200px]]


{{STRUCTURE_3hzn|  PDB=3hzn  |  SCENE=  }}
==Structure of the Salmonella typhimurium nfnB dihydropteridine reductase==
 
<StructureSection load='3hzn' size='340' side='right'caption='[[3hzn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
===Structure of the Salmonella typhimurium nfnB dihydropteridine reductase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3hzn]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HZN FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
[[3hzn]] is a 8 chain structure of [[Nitroreductase]] with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZN OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzn OCA], [https://pdbe.org/3hzn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hzn RCSB], [https://www.ebi.ac.uk/pdbsum/3hzn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzn ProSAT], [https://www.topsan.org/Proteins/CSGID/3hzn TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NFSB_SALTY NFSB_SALTY] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hzn ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Nitroreductase|Nitroreductase]]
*[[Nitroreductase 3D structures|Nitroreductase 3D structures]]
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
__TOC__
[[Category: Anderson, S M.]]
</StructureSection>
[[Category: Anderson, W F.]]
[[Category: Large Structures]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Onopriyenko, O.]]
[[Category: Anderson SM]]
[[Category: Savchenko, A.]]
[[Category: Anderson WF]]
[[Category: Skarina, T.]]
[[Category: Onopriyenko O]]
[[Category: Wawrzak, Z.]]
[[Category: Savchenko A]]
[[Category: 3 layer sandwich]]
[[Category: Skarina T]]
[[Category: Alpha and beta protein]]
[[Category: Wawrzak Z]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Flavoprotein]]
[[Category: Fmn]]
[[Category: Fmn-dependent nitroreductase like]]
[[Category: Nad]]
[[Category: Nadp]]
[[Category: Oxidoreductase]]
[[Category: Structural genomic]]
Retrieved from "https://proteopedia.org/3hzn"