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[[Image:3lez.png|left|200px]]


{{STRUCTURE_3lez|  PDB=3lez  |  SCENE=  }}
==Crystal structure of a halotolerant bacterial beta-lactamase==
 
<StructureSection load='3lez' size='340' side='right'caption='[[3lez]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
===Crystal structure of a halotolerant bacterial beta-lactamase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3lez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oceanobacillus_iheyensis Oceanobacillus iheyensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LEZ FirstGlance]. <br>
{{ABSTRACT_PUBMED_20000704}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lez OCA], [https://pdbe.org/3lez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lez RCSB], [https://www.ebi.ac.uk/pdbsum/3lez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lez ProSAT]</span></td></tr>
[[3lez]] is a 1 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Oceanobacillus_iheyensis Oceanobacillus iheyensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LEZ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8EMP8_OCEIH Q8EMP8_OCEIH]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/le/3lez_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lez ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Beta-lactamase|Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020000704</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Beta-lactamase]]
[[Category: Oceanobacillus iheyensis]]
[[Category: Oceanobacillus iheyensis]]
[[Category: Smith, C A.]]
[[Category: Smith CA]]
[[Category: Vakulenko, S B.]]
[[Category: Vakulenko SB]]
[[Category: Antibiotic resistance]]
[[Category: Beta-lactamase]]
[[Category: Deep-sea bacterium]]
[[Category: Halotolerant]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/3lez"