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[[Image:5pal.png|left|200px]]


{{STRUCTURE_5pal|  PDB=5pal  |  SCENE=  }}
==CRYSTAL STRUCTURE OF THE UNIQUE PARVALBUMIN COMPONENT FROM MUSCLE OF THE LEOPARD SHARK (TRIAKIS SEMIFASCIATA). THE FIRST X-RAY STUDY OF AN ALPHA-PARVALBUMIN==
 
<StructureSection load='5pal' size='340' side='right'caption='[[5pal]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
===CRYSTAL STRUCTURE OF THE UNIQUE PARVALBUMIN COMPONENT FROM MUSCLE OF THE LEOPARD SHARK (TRIAKIS SEMIFASCIATA). THE FIRST X-RAY STUDY OF AN ALPHA-PARVALBUMIN===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5pal]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Triakis_semifasciata Triakis semifasciata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5PAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5PAL FirstGlance]. <br>
{{ABSTRACT_PUBMED_1542115}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5pal OCA], [https://pdbe.org/5pal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5pal RCSB], [https://www.ebi.ac.uk/pdbsum/5pal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5pal ProSAT]</span></td></tr>
[[5pal]] is a 1 chain structure of [[Parvalbumin]] with sequence from [http://en.wikipedia.org/wiki/Triakis_semifasciata Triakis semifasciata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5PAL OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRVA_TRISE PRVA_TRISE] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pa/5pal_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=5pal ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Parvalbumin|Parvalbumin]]
*[[Parvalbumin|Parvalbumin]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:001542115</ref><ref group="xtra">PMID:019756040</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Triakis semifasciata]]
[[Category: Triakis semifasciata]]
[[Category: Declercq, J P.]]
[[Category: Declercq J-P]]
[[Category: Parello, J.]]
[[Category: Parello J]]
[[Category: Rambaud, J.]]
[[Category: Rambaud J]]
[[Category: Roquet, F.]]
[[Category: Roquet F]]
[[Category: Tinant, B.]]
[[Category: Tinant B]]
[[Category: Calcium-binding protein]]
Retrieved from "https://proteopedia.org/5pal"