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[[Image:3i1a.png|left|200px]]


{{STRUCTURE_3i1a|  PDB=3i1a  |  SCENE=  }}
==Crystal Structure of apo Spectinomycin Phosphotransferase, APH(9)-Ia==
 
<StructureSection load='3i1a' size='340' side='right'caption='[[3i1a]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
===Crystal Structure of apo Spectinomycin Phosphotransferase, APH(9)-Ia===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3i1a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_serogroup_1 Legionella pneumophila serogroup 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I1A FirstGlance]. <br>
{{ABSTRACT_PUBMED_20089863}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i1a OCA], [https://pdbe.org/3i1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i1a RCSB], [https://www.ebi.ac.uk/pdbsum/3i1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i1a ProSAT]</span></td></tr>
[[3i1a]] is a 2 chain structure of [[Phosphotransferase]] with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I1A OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/O06916_LEGPN O06916_LEGPN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/3i1a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i1a ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphotransferase|Phosphotransferase]]
*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020089863</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Legionella pneumophila]]
[[Category: Legionella pneumophila serogroup 1]]
[[Category: Berghuis, A M.]]
[[Category: Berghuis AM]]
[[Category: Fong, D H.]]
[[Category: Fong DH]]
[[Category: Hwang, J.]]
[[Category: Hwang J]]
[[Category: Lemke, C T.]]
[[Category: Lemke CT]]
[[Category: Xiong, B.]]
[[Category: Xiong B]]
[[Category: Aminoglycoside phosphotransferase]]
[[Category: Antibiotic resistance]]
[[Category: Protein kinase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3i1a"