3n3y: Difference between revisions
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==Crystal structure of Thymidylate Synthase X (ThyX) from Helicobacter pylori with FAD and dUMP at 2.31A resolution== | |||
<StructureSection load='3n3y' size='340' side='right'caption='[[3n3y]], [[Resolution|resolution]] 2.31Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3n3y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_SS1 Helicobacter pylori SS1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N3Y FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.307Å</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
[[3n3y]] is a 4 chain structure | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n3y OCA], [https://pdbe.org/3n3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n3y RCSB], [https://www.ebi.ac.uk/pdbsum/3n3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n3y ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q5UVJ4_HELPX Q5UVJ4_HELPX] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.[HAMAP-Rule:MF_01408] | |||
==See Also== | ==See Also== | ||
*[[Thymidylate synthase|Thymidylate synthase]] | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | ||
[[Category: Helicobacter pylori]] | __TOC__ | ||
[[Category: Chen | </StructureSection> | ||
[[Category: Chen | [[Category: Helicobacter pylori SS1]] | ||
[[Category: Jiang | [[Category: Large Structures]] | ||
[[Category: Shen | [[Category: Chen J]] | ||
[[Category: Wang | [[Category: Chen L]] | ||
[[Category: Wang | [[Category: Jiang H]] | ||
[[Category: Shen X]] | |||
[[Category: Wang K]] | |||
[[Category: Wang Q]] | |||
Latest revision as of 09:58, 14 February 2024
Crystal structure of Thymidylate Synthase X (ThyX) from Helicobacter pylori with FAD and dUMP at 2.31A resolution
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