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[[Image:3tjf.png|left|200px]]


{{STRUCTURE_3tjf|  PDB=3tjf  |  SCENE=  }}
==Crystal Structure of human peroxiredoxin IV C51A mutant in reduced form==
 
<StructureSection load='3tjf' size='340' side='right'caption='[[3tjf]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
===Crystal Structure of human peroxiredoxin IV C51A mutant in reduced form===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3tjf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TJF FirstGlance]. <br>
{{ABSTRACT_PUBMED_21994946}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tjf OCA], [https://pdbe.org/3tjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tjf RCSB], [https://www.ebi.ac.uk/pdbsum/3tjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tjf ProSAT]</span></td></tr>
[[3tjf]] is a 5 chain structure of [[Peroxiredoxin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TJF OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRDX4_HUMAN PRDX4_HUMAN] Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.<ref>PMID:9388242</ref>


==See Also==
==See Also==
*[[Peroxiredoxin|Peroxiredoxin]]
*[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:021994946</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peroxiredoxin]]
[[Category: Large Structures]]
[[Category: Bulleid, N J.]]
[[Category: Bulleid NJ]]
[[Category: Cao, Z.]]
[[Category: Cao Z]]
[[Category: Cogdell, R J.]]
[[Category: Cogdell RJ]]
[[Category: Roszak, A W.]]
[[Category: Roszak AW]]
[[Category: Tavender, T J.]]
[[Category: Tavender TJ]]
[[Category: Endoplasmic reticulum]]
[[Category: Oxidoreductase]]
[[Category: Sulfenylation]]
[[Category: Thioredoxin fold]]

Latest revision as of 13:30, 14 March 2024

Crystal Structure of human peroxiredoxin IV C51A mutant in reduced form

3tjf, resolution 2.04Å

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