1cun: Difference between revisions

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[[Image:1cun.png|left|200px]]


{{STRUCTURE_1cun|  PDB=1cun  |  SCENE=  }}
==CRYSTAL STRUCTURE OF REPEATS 16 AND 17 OF CHICKEN BRAIN ALPHA SPECTRIN==
 
<StructureSection load='1cun' size='340' side='right'caption='[[1cun]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===CRYSTAL STRUCTURE OF REPEATS 16 AND 17 OF CHICKEN BRAIN ALPHA SPECTRIN===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1cun]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CUN FirstGlance]. <br>
{{ABSTRACT_PUBMED_10481916}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cun OCA], [https://pdbe.org/1cun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cun RCSB], [https://www.ebi.ac.uk/pdbsum/1cun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cun ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1cun]] is a 3 chain structure of [[Spectrin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUN OCA].  
== Function ==
[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/1cun_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cun ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Spectrin|Spectrin]]
*[[Spectrin 3D structures|Spectrin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010481916</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Grum, V L.]]
[[Category: Large Structures]]
[[Category: Li, D.]]
[[Category: Grum VL]]
[[Category: MacDonald, R I.]]
[[Category: Li D]]
[[Category: Mondragon, A.]]
[[Category: MacDonald RI]]
[[Category: 2 tandem 3-helix coiled- coil]]
[[Category: Mondragon A]]
[[Category: Alpha helical linker region]]
[[Category: Structural protein]]
[[Category: Two repeats of spectrin]]

Latest revision as of 06:45, 7 February 2024

CRYSTAL STRUCTURE OF REPEATS 16 AND 17 OF CHICKEN BRAIN ALPHA SPECTRIN

1cun, resolution 2.00Å

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