3i0x: Difference between revisions

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[[Image:3i0x.png|left|200px]]


{{STRUCTURE_3i0x|  PDB=3i0x  |  SCENE=  }}
==Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing adenine opposite to 8-oxoG==
 
<StructureSection load='3i0x' size='340' side='right'caption='[[3i0x]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing adenine opposite to 8-oxoG===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3i0x]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I0X FirstGlance]. <br>
{{ABSTRACT_PUBMED_19747886}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8OG:8-OXO-2-DEOXY-GUANOSINE-5-MONOPHOSPHATE'>8OG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i0x OCA], [https://pdbe.org/3i0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i0x RCSB], [https://www.ebi.ac.uk/pdbsum/3i0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i0x ProSAT]</span></td></tr>
[[3i0x]] is a 3 chain structure of [[DNA glycosylate]] with sequence from [http://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I0X OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q97FM4_CLOAB Q97FM4_CLOAB]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i0/3i0x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i0x ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[DNA glycosylate|DNA glycosylate]]
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:019747886</ref><references group="xtra"/>
[[Category: Clostridium acetobutylicum]]
[[Category: Clostridium acetobutylicum]]
[[Category: Doublie, S.]]
[[Category: Large Structures]]
[[Category: Faucher, F.]]
[[Category: Doublie S]]
[[Category: 8-oxog]]
[[Category: Faucher F]]
[[Category: 8oxog]]
[[Category: Adenine]]
[[Category: Cacogg]]
[[Category: Dna]]
[[Category: Glycosylase]]
[[Category: Hydrolase]]
[[Category: Lyase-dna complex]]
[[Category: Ogg]]

Latest revision as of 10:02, 21 February 2024

Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing adenine opposite to 8-oxoG

3i0x, resolution 1.80Å

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