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[[Image:2au3.png|left|200px]]


{{STRUCTURE_2au3|  PDB=2au3  |  SCENE=  }}
==Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains)==
 
<StructureSection load='2au3' size='340' side='right'caption='[[2au3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2au3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AU3 FirstGlance]. <br>
{{ABSTRACT_PUBMED_16285921}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2au3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2au3 OCA], [https://pdbe.org/2au3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2au3 RCSB], [https://www.ebi.ac.uk/pdbsum/2au3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2au3 ProSAT]</span></td></tr>
[[2au3]] is a 1 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AU3 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DNAG_AQUAE DNAG_AQUAE] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.[HAMAP-Rule:MF_00974]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/au/2au3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2au3 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016285921</ref><references group="xtra"/>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Berger, J M.]]
[[Category: Large Structures]]
[[Category: Corn, J E.]]
[[Category: Berger JM]]
[[Category: Hura, G L.]]
[[Category: Corn JE]]
[[Category: Pease, P J.]]
[[Category: Hura GL]]
[[Category: Dna replication]]
[[Category: Pease PJ]]
[[Category: Rna polymerase]]
[[Category: Toprim]]
[[Category: Transferase]]
[[Category: Zinc ribbon]]
Retrieved from "https://proteopedia.org/2au3"