3rb9: Difference between revisions
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==Crystal structure of the M. tuberculosis beta clamp== | |||
<StructureSection load='3rb9' size='340' side='right'caption='[[3rb9]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3rb9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RB9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rb9 OCA], [https://pdbe.org/3rb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rb9 RCSB], [https://www.ebi.ac.uk/pdbsum/3rb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rb9 ProSAT]</span></td></tr> | ||
[[3rb9]] is a 2 chain structure | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DPO3B_MYCTU DPO3B_MYCTU] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity). | |||
==See Also== | ==See Also== | ||
*[[DNA polymerase|DNA polymerase]] | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | ||
[[Category: | __TOC__ | ||
[[Category: Mycobacterium tuberculosis]] | </StructureSection> | ||
[[Category: Kukshal | [[Category: Large Structures]] | ||
[[Category: Ramachandran | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Kukshal V]] | |||
[[Category: Ramachandran R]] | |||
Latest revision as of 08:35, 20 March 2024
Crystal structure of the M. tuberculosis beta clamp
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