1p0c: Difference between revisions

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[[Image:1p0c.png|left|200px]]


{{STRUCTURE_1p0c|  PDB=1p0c  |  SCENE=  }}
==Crystal Structure of the NADP(H)-Dependent Vertebrate Alcohol Dehydrogenase (ADH8)==
 
<StructureSection load='1p0c' size='340' side='right'caption='[[1p0c]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal Structure of the NADP(H)-Dependent Vertebrate Alcohol Dehydrogenase (ADH8)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1p0c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pelophylax_perezi Pelophylax perezi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P0C FirstGlance]. <br>
{{ABSTRACT_PUBMED_12818203}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0c OCA], [https://pdbe.org/1p0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p0c RCSB], [https://www.ebi.ac.uk/pdbsum/1p0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0c ProSAT]</span></td></tr>
[[1p0c]] is a 2 chain structure of [[Alcohol dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Pelophylax_perezi Pelophylax perezi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0C OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/ADH8_PELPE ADH8_PELPE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/1p0c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p0c ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Alcohol dehydrogenase|Alcohol dehydrogenase]]
*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:012818203</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Pelophylax perezi]]
[[Category: Pelophylax perezi]]
[[Category: Farres, J.]]
[[Category: Farres J]]
[[Category: Fita, I.]]
[[Category: Fita I]]
[[Category: Ochoa, W F.]]
[[Category: Ochoa WF]]
[[Category: Pares, X.]]
[[Category: Pares X]]
[[Category: Rosell, A.]]
[[Category: Rosell A]]
[[Category: Valencia, E.]]
[[Category: Valencia E]]
[[Category: Adh topology]]
[[Category: Oxidoreductase]]

Latest revision as of 08:04, 14 February 2024

Crystal Structure of the NADP(H)-Dependent Vertebrate Alcohol Dehydrogenase (ADH8)

1p0c, resolution 2.20Å

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