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[[Image:1phz.png|left|200px]]


{{STRUCTURE_1phz|  PDB=1phz  |  SCENE=  }}
==STRUCTURE OF PHOSPHORYLATED PHENYLALANINE HYDROXYLASE==
 
<StructureSection load='1phz' size='340' side='right'caption='[[1phz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===STRUCTURE OF PHOSPHORYLATED PHENYLALANINE HYDROXYLASE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1phz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The January 2005 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phenylalanine Hydroxylase''  by Shuchismita Dutta and David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2005_1 10.2210/rcsb_pdb/mom_2005_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PHZ FirstGlance]. <br>
{{ABSTRACT_PUBMED_10331871}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1phz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1phz OCA], [https://pdbe.org/1phz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1phz RCSB], [https://www.ebi.ac.uk/pdbsum/1phz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1phz ProSAT]</span></td></tr>
[[1phz]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The January 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phenylalanine Hydroxylase''  by Shuchismita Dutta and David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_1 10.2210/rcsb_pdb/mom_2005_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHZ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PH4H_RAT PH4H_RAT]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/1phz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1phz ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]]
*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010331871</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Phenylalanine 4-monooxygenase]]
[[Category: Phenylalanine Hydroxylase]]
[[Category: Phenylalanine Hydroxylase]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Cotton, R G.]]
[[Category: Cotton RG]]
[[Category: House, C M.]]
[[Category: House CM]]
[[Category: Jennings, I G.]]
[[Category: Jennings IG]]
[[Category: Kemp, B E.]]
[[Category: Kemp BE]]
[[Category: Kobe, B.]]
[[Category: Kobe B]]
[[Category: Michell, B J.]]
[[Category: Michell BJ]]
[[Category: Allosteric regulation]]
[[Category: Aromatic amino acid hydroxylase]]
[[Category: Intrasteric regulation]]
[[Category: Oxidoreductase]]
[[Category: Phenylalanine hydroxylase]]
[[Category: Phosphorylation]]
Retrieved from "https://proteopedia.org/1phz"