3kms: Difference between revisions

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[[Image:3kms.png|left|200px]]


{{STRUCTURE_3kms|  PDB=3kms  |  SCENE=  }}
==G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure==
 
<StructureSection load='3kms' size='340' side='right'caption='[[3kms]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3kms]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot_and_mouth_disease_virus_C Foot and mouth disease virus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KMS FirstGlance]. <br>
{{ABSTRACT_PUBMED_20392853}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kms OCA], [https://pdbe.org/3kms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kms RCSB], [https://www.ebi.ac.uk/pdbsum/3kms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kms ProSAT]</span></td></tr>
[[3kms]] is a 3 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_-_type_c Foot-and-mouth disease virus - type c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KMS OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9QCE3_9PICO Q9QCE3_9PICO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/3kms_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kms ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020392853</ref><references group="xtra"/>
[[Category: Foot and mouth disease virus C]]
[[Category: Foot-and-mouth disease virus - type c]]
[[Category: Large Structures]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Ferrer-Orta C]]
[[Category: Ferrer-Orta, C.]]
[[Category: Perez-Luque R]]
[[Category: Perez-Luque, R.]]
[[Category: Verdaguer N]]
[[Category: Verdaguer, N.]]
[[Category: 3d]]
[[Category: Foot-and mouth disease virus]]
[[Category: Polymerase]]
[[Category: Ribavirin]]
[[Category: Rna dependent rna polymerase]]
[[Category: Transferase-rna complex]]
Retrieved from "https://proteopedia.org/3kms"