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[[Image:1zbf.png|left|200px]]


{{STRUCTURE_1zbf|  PDB=1zbf  |  SCENE=  }}
==Crystal structure of B. halodurans RNase H catalytic domain mutant D132N==
 
<StructureSection load='1zbf' size='340' side='right'caption='[[1zbf]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
===Crystal structure of B. halodurans RNase H catalytic domain mutant D132N===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1zbf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZBF FirstGlance]. <br>
{{ABSTRACT_PUBMED_15989951}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zbf OCA], [https://pdbe.org/1zbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zbf RCSB], [https://www.ebi.ac.uk/pdbsum/1zbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zbf ProSAT]</span></td></tr>
[[1zbf]] is a 1 chain structure of [[Ribonuclease]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZBF OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNH1_HALH5 RNH1_HALH5] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<ref>PMID:15989951</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zb/1zbf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zbf ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:015989951</ref><references group="xtra"/>
__TOC__
[[Category: Bacillus halodurans]]
</StructureSection>
[[Category: Ribonuclease H]]
[[Category: Alkalihalobacillus halodurans C-125]]
[[Category: Crouch, R J.]]
[[Category: Large Structures]]
[[Category: Gaidamakov, S A.]]
[[Category: Crouch RJ]]
[[Category: Nowotny, M.]]
[[Category: Gaidamakov SA]]
[[Category: Yang, W.]]
[[Category: Nowotny M]]
[[Category: Dde motif]]
[[Category: Yang W]]
[[Category: Hydrolase]]
[[Category: Rna/dna hybrid]]
[[Category: Rnase h]]
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