1mkp: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(9 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1mkp.png|left|200px]]


{{STRUCTURE_1mkp|  PDB=1mkp  |  SCENE=  }}
==CRYSTAL STRUCTURE OF PYST1 (MKP3)==
 
<StructureSection load='1mkp' size='340' side='right'caption='[[1mkp]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
===CRYSTAL STRUCTURE OF PYST1 (MKP3)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1mkp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MKP FirstGlance]. <br>
{{ABSTRACT_PUBMED_10048930}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mkp OCA], [https://pdbe.org/1mkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mkp RCSB], [https://www.ebi.ac.uk/pdbsum/1mkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mkp ProSAT]</span></td></tr>
[[1mkp]] is a 1 chain structure of [[MAP kinase phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKP OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DUS6_HUMAN DUS6_HUMAN] Inactivates MAP kinases. Has a specificity for the ERK family.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/1mkp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mkp ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[MAP kinase phosphatase|MAP kinase phosphatase]]
*[[MAP kinase phosphatase|MAP kinase phosphatase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010048930</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Dowd, S.]]
[[Category: Large Structures]]
[[Category: Keyse, S.]]
[[Category: Dowd S]]
[[Category: Mcdonald, N Q.]]
[[Category: Keyse S]]
[[Category: Stewart, A E.]]
[[Category: Mcdonald NQ]]
[[Category: Hydrolase]]
[[Category: Stewart AE]]
Retrieved from "https://proteopedia.org/1mkp"