2p2t: Difference between revisions

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[[Image:2p2t.png|left|200px]]


{{STRUCTURE_2p2t|  PDB=2p2t  |  SCENE=  }}
==Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74==
 
<StructureSection load='2p2t' size='340' side='right'caption='[[2p2t]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2p2t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P2T FirstGlance]. <br>
{{ABSTRACT_PUBMED_17570393}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p2t OCA], [https://pdbe.org/2p2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p2t RCSB], [https://www.ebi.ac.uk/pdbsum/2p2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p2t ProSAT]</span></td></tr>
[[2p2t]] is a 2 chain structure of [[Dynein]] with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P2T OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYL1_DROME DYL1_DROME] Acts as a non-catalytic accessory component of a dynein complex (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p2/2p2t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p2t ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Dynein|Dynein]]
*[[Dynein 3D structures|Dynein 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:017570393</ref><references group="xtra"/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Barbar, E.]]
[[Category: Large Structures]]
[[Category: Benison, G.]]
[[Category: Barbar E]]
[[Category: Karplus, P A.]]
[[Category: Benison G]]
[[Category: Protein - peptide complex]]
[[Category: Karplus PA]]
[[Category: Transport protein]]