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[[Image:2aus.png|left|200px]]


{{STRUCTURE_2aus|  PDB=2aus  |  SCENE=  }}
==Crystal structure of the archaeal box H/ACA sRNP Nop10-Cbf5 complex==
 
<StructureSection load='2aus' size='340' side='right'caption='[[2aus]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===Crystal structure of the archaeal box H/ACA sRNP Nop10-Cbf5 complex===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2aus]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AUS FirstGlance]. <br>
{{ABSTRACT_PUBMED_16456033}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aus OCA], [https://pdbe.org/2aus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aus RCSB], [https://www.ebi.ac.uk/pdbsum/2aus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aus ProSAT]</span></td></tr>
[[2aus]] is a 4 chain structure of [[TRNA pseudouridine synthase]] with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AUS OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRUB_PYRAB TRUB_PYRAB] Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/au/2aus_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aus ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[TRNA pseudouridine synthase|TRNA pseudouridine synthase]]
*[[Pseudouridine synthase 3D structures|Pseudouridine synthase 3D structures]]
 
*[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:016456033</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus abyssi]]
[[Category: Pyrococcus abyssi]]
[[Category: Branlant, C.]]
[[Category: Branlant C]]
[[Category: Charpentier, B.]]
[[Category: Charpentier B]]
[[Category: Charron, C.]]
[[Category: Charron C]]
[[Category: Fourmann, J B.]]
[[Category: Fourmann J-B]]
[[Category: Godard, F.]]
[[Category: Godard F]]
[[Category: Manival, X.]]
[[Category: Manival X]]
[[Category: Isomerase]]
[[Category: Isomerase-structural protein complex]]
[[Category: Structural protein]]
Retrieved from "https://proteopedia.org/2aus"