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[[Image:2rhl.png|left|200px]]


{{STRUCTURE_2rhl|  PDB=2rhl  |  SCENE=  }}
==Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP==
 
<StructureSection load='2rhl' size='340' side='right'caption='[[2rhl]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
===Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2rhl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RHL FirstGlance]. <br>
{{ABSTRACT_PUBMED_19383143}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhl OCA], [https://pdbe.org/2rhl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rhl RCSB], [https://www.ebi.ac.uk/pdbsum/2rhl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rhl ProSAT]</span></td></tr>
[[2rhl]] is a 2 chain structure of [[Cell division protein Ftsz]] and [[Tubulin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHL OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/FTSZ_BACSU FTSZ_BACSU] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.<ref>PMID:15317782</ref> <ref>PMID:16159787</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/2rhl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rhl ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cell division protein Ftsz|Cell division protein Ftsz]]
*[[Cell division protein 3D structures|Cell division protein 3D structures]]
*[[Tubulin|Tubulin]]
== References ==
 
<references/>
==Reference==
__TOC__
<ref group="xtra">PMID:019383143</ref><references group="xtra"/>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: ATCG3D, Accelerated Technologies Center for Gene to 3D Structure.]]
[[Category: Large Structures]]
[[Category: Burgin, A.]]
[[Category: Burgin A]]
[[Category: Halloran, Z.]]
[[Category: Halloran Z]]
[[Category: Hjerrild, K.]]
[[Category: Hjerrild K]]
[[Category: Lovell, S.]]
[[Category: Lovell S]]
[[Category: Sheridan, D.]]
[[Category: Sheridan D]]
[[Category: Stewart, L.]]
[[Category: Stewart L]]
[[Category: Accelerated technologies center for gene to 3d structure]]
[[Category: Atcg3d]]
[[Category: Cell cycle]]
[[Category: Cell division protein]]
[[Category: Gtp-binding]]
[[Category: Gtpase]]
[[Category: Polymerization]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Tubulin homolog]]

Latest revision as of 09:22, 21 February 2024

Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP

2rhl, resolution 2.45Å

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