2cyb: Difference between revisions

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[[Image:2cyb.png|left|200px]]


{{STRUCTURE_2cyb|  PDB=2cyb  |  SCENE=  }}
==Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Archaeoglobus fulgidus==
 
<StructureSection load='2cyb' size='340' side='right'caption='[[2cyb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Archaeoglobus fulgidus===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2cyb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYB FirstGlance]. <br>
{{ABSTRACT_PUBMED_16325203}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cyb OCA], [https://pdbe.org/2cyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cyb RCSB], [https://www.ebi.ac.uk/pdbsum/2cyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cyb ProSAT], [https://www.topsan.org/Proteins/RSGI/2cyb TOPSAN]</span></td></tr>
[[2cyb]] is a 2 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYB OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYY_ARCFU SYY_ARCFU] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity).[HAMAP-Rule:MF_02008]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/2cyb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cyb ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016325203</ref><references group="xtra"/>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Kobayashi, T.]]
[[Category: Kobayashi T]]
[[Category: Kuratani, M.]]
[[Category: Kuratani M]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Sakai H]]
[[Category: Sakai, H.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Takahashi M]]
[[Category: Takahashi, M.]]
[[Category: Terada T]]
[[Category: Terada, T.]]
[[Category: Yanagisawa T]]
[[Category: Yanagisawa, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rossmann-fold]]
[[Category: Rsgi]]
[[Category: Structural genomic]]

Latest revision as of 13:45, 13 March 2024

Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Archaeoglobus fulgidus

2cyb, resolution 1.80Å

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