2cv5: Difference between revisions

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[[Image:2cv5.png|left|200px]]


{{STRUCTURE_2cv5|  PDB=2cv5  |  SCENE=  }}
==Crystal structure of human nucleosome core particle==
 
<StructureSection load='2cv5' size='340' side='right'caption='[[2cv5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal structure of human nucleosome core particle===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2cv5]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CV5 FirstGlance]. <br>
{{ABSTRACT_PUBMED_15951514}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cv5 OCA], [https://pdbe.org/2cv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cv5 RCSB], [https://www.ebi.ac.uk/pdbsum/2cv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cv5 ProSAT]</span></td></tr>
[[2cv5]] is a 10 chain structure of [[Histone]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CV5 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/H31_HUMAN H31_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cv/2cv5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cv5 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Histone|Histone]]
*[[Histone 3D structures|Histone 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:015951514</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kajimura, N.]]
[[Category: Large Structures]]
[[Category: Morikawa, K.]]
[[Category: Kajimura N]]
[[Category: Tate, S.]]
[[Category: Morikawa K]]
[[Category: Tsunaka, Y.]]
[[Category: Tate S]]
[[Category: Human nucleosome structure]]
[[Category: Tsunaka Y]]
[[Category: Metal binding site]]
[[Category: Structural protein-dna complex]]
[[Category: Supercoiled dna path]]
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