3htz: Difference between revisions

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[[Image:3htz.png|left|200px]]


{{STRUCTURE_3htz|  PDB=3htz  |  SCENE=  }}
==Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined==
 
<StructureSection load='3htz' size='340' side='right'caption='[[3htz]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3htz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HTZ FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3htz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3htz OCA], [https://pdbe.org/3htz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3htz RCSB], [https://www.ebi.ac.uk/pdbsum/3htz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3htz ProSAT]</span></td></tr>
[[3htz]] is a 1 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HTZ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYA_AQUAE SYA_AQUAE] Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity).[HAMAP-Rule:MF_00036]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/3htz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3htz ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
[[Category: Alanine--tRNA ligase]]
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Guo, M.]]
[[Category: Large Structures]]
[[Category: Schimmel, P.]]
[[Category: Guo M]]
[[Category: Swairjo, M A.]]
[[Category: Schimmel P]]
[[Category: Adenosine triphosphate]]
[[Category: Swairjo MA]]
[[Category: Alanine-trna ligase]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Atp-binding]]
[[Category: Binding site]]
[[Category: Genetic code]]
[[Category: Ligase]]
[[Category: Nucleotide-binding]]
[[Category: Protein biosynthesis]]
[[Category: Protein conformation]]

Latest revision as of 07:31, 6 September 2023

Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined

3htz, resolution 2.50Å

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