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[[Image:2cks.png|left|200px]]


{{STRUCTURE_2cks|  PDB=2cks  |  SCENE=  }}
==X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THERMOBIFIDA FUSCA ENDOGLUCANASE CEL5A (E5)==
 
<StructureSection load='2cks' size='340' side='right'caption='[[2cks]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
===X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THERMOBIFIDA FUSCA ENDOGLUCANASE CEL5A (E5)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2cks]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CKS FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[2cks]] is a 2 chain structure of [[Glucanase]] with sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CKS OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cks OCA], [https://pdbe.org/2cks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cks RCSB], [https://www.ebi.ac.uk/pdbsum/2cks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cks ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GUN5_THEFU GUN5_THEFU]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/2cks_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cks ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Glucanase|Glucanase]]
*[[Glucanase 3D structures|Glucanase 3D structures]]
[[Category: Cellulase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermobifida fusca]]
[[Category: Thermobifida fusca]]
[[Category: Bergfors, T.]]
[[Category: Bergfors T]]
[[Category: Berglund, G I.]]
[[Category: Berglund GI]]
[[Category: Gross, L S.]]
[[Category: Gross LS]]
[[Category: Gualfetti, P J.]]
[[Category: Gualfetti PJ]]
[[Category: Mitchinson, C.]]
[[Category: Mitchinson C]]
[[Category: Requadt, C.]]
[[Category: Requadt C]]
[[Category: Saldajeno, M.]]
[[Category: Saldajeno M]]
[[Category: Sandgren, M.]]
[[Category: Sandgren M]]
[[Category: Shaw, A.]]
[[Category: Shaw A]]
[[Category: Carbohydrate metabolism]]
[[Category: Cellulose degradation]]
[[Category: Endoglucanase]]
[[Category: Glycosidase]]
[[Category: Glycoside hydrolase family 5]]
[[Category: Hydrolase]]
[[Category: Polysaccharide degradation]]
[[Category: Thermobifida fusca e5]]