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[[Image:4df4.png|left|200px]]


{{STRUCTURE_4df4|  PDB=4df4  |  SCENE=  }}
==Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 7-(N-(10-hydroxydecanoyl)-aminopentinyl)-7-deaza-2 -dATP==
 
<StructureSection load='4df4' size='340' side='right'caption='[[4df4]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 7-(N-(10-hydroxydecanoyl)-aminopentinyl)-7-deaza-2 -dATP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4df4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DF4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_22475415}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0L3:7-{2-DEOXY-5-O-[(S)-HYDROXY{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-{5-[(10-HYDROXYDECANOYL)AMINO]PENT-1-YN-1-YL}-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE'>0L3</scene>, <scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4df4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4df4 OCA], [https://pdbe.org/4df4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4df4 RCSB], [https://www.ebi.ac.uk/pdbsum/4df4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4df4 ProSAT]</span></td></tr>
[[4df4]] is a 3 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DF4 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPO1_THEAQ DPO1_THEAQ]


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022475415</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Baccaro, A.]]
[[Category: Baccaro A]]
[[Category: Bergen, K.]]
[[Category: Bergen K]]
[[Category: Diederichs, K.]]
[[Category: Diederichs K]]
[[Category: Marx, A.]]
[[Category: Marx A]]
[[Category: Steck, A.]]
[[Category: Steck A]]
[[Category: Struett, S.]]
[[Category: Struett S]]
[[Category: Welte, W.]]
[[Category: Welte W]]
[[Category: Dna polymerase]]
[[Category: Transferase-dna complex]]