2gze: Difference between revisions
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==Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y55A)== | |||
<StructureSection load='2gze' size='340' side='right'caption='[[2gze]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2gze]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GZE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gze OCA], [https://pdbe.org/2gze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gze RCSB], [https://www.ebi.ac.uk/pdbsum/2gze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gze ProSAT]</span></td></tr> | ||
[[2gze]] | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IMM9_ECOLX IMM9_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/2gze_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gze ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Colicin|Colicin]] | *[[Colicin 3D structures|Colicin 3D structures]] | ||
*[[Colicin | *[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Hemmings AM]] | ||
[[Category: Hemmings | [[Category: Kleanthous C]] | ||
[[Category: Kleanthous | [[Category: Kolade OO]] | ||
[[Category: Kolade | [[Category: Kuhlmann UC]] | ||
[[Category: Kuhlmann | [[Category: Santi PS]] | ||
[[Category: Santi | |||
Latest revision as of 09:49, 30 August 2023
Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y55A)
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