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[[Image:1qtm.png|left|200px]]


{{STRUCTURE_1qtm|  PDB=1qtm  |  SCENE=  }}
==DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS==
 
<StructureSection load='1qtm' size='340' side='right'caption='[[1qtm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
===DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1qtm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QTM FirstGlance]. <br>
{{ABSTRACT_PUBMED_10449720}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DT:3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>2DT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qtm OCA], [https://pdbe.org/1qtm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qtm RCSB], [https://www.ebi.ac.uk/pdbsum/1qtm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qtm ProSAT]</span></td></tr>
[[1qtm]] is a 3 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QTM OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPO1_THEAQ DPO1_THEAQ]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qt/1qtm_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qtm ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010449720</ref><ref group="xtra">PMID:010458614</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Li, Y.]]
[[Category: Li Y]]
[[Category: Mitaxov, V.]]
[[Category: Mitaxov V]]
[[Category: Waksman, G.]]
[[Category: Waksman G]]
[[Category: Closed]]
[[Category: Ddttp]]
[[Category: Polymerase/dna]]
[[Category: Protein-dna complex]]
[[Category: Transferase-dna complex]]
Retrieved from "https://proteopedia.org/1qtm"