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[[Image:2dto.png|left|200px]]


{{STRUCTURE_2dto|  PDB=2dto  |  SCENE=  }}
==Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 Complexed with ATP and Biotin==
 
<StructureSection load='2dto' size='340' side='right'caption='[[2dto]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
===Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 Complexed with ATP and Biotin===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2dto]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTO FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[2dto]] is a 2 chain structure of [[Biotin Protein Ligase]] with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTO OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dto OCA], [https://pdbe.org/2dto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dto RCSB], [https://www.ebi.ac.uk/pdbsum/2dto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dto ProSAT], [https://www.topsan.org/Proteins/RSGI/2dto TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O57883_PYRHO O57883_PYRHO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dto_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dto ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Biotin Protein Ligase|Biotin Protein Ligase]]
*[[Biotin Protein Ligase 3D structures|Biotin Protein Ligase 3D structures]]
[[Category: Pyrococcus horikoshii]]
__TOC__
[[Category: Bagautdinov, B.]]
</StructureSection>
[[Category: Kunishima, N.]]
[[Category: Large Structures]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Biotin biosynthesis]]
[[Category: Bagautdinov B]]
[[Category: Dimer]]
[[Category: Kunishima N]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]

Latest revision as of 00:52, 21 November 2024

Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 Complexed with ATP and Biotin

2dto, resolution 1.50Å

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