1u5p: Difference between revisions

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[[Image:1u5p.png|left|200px]]


{{STRUCTURE_1u5p|  PDB=1u5p  |  SCENE=  }}
==Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin==
 
<StructureSection load='1u5p' size='340' side='right'caption='[[1u5p]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1u5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U5P FirstGlance]. <br>
{{ABSTRACT_PUBMED_15522301}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u5p OCA], [https://pdbe.org/1u5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u5p RCSB], [https://www.ebi.ac.uk/pdbsum/1u5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u5p ProSAT]</span></td></tr>
[[1u5p]] is a 1 chain structure of [[Spectrin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5P OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u5/1u5p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u5p ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Spectrin|Spectrin]]
*[[Spectrin 3D structures|Spectrin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:015522301</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Kusunoki, H.]]
[[Category: Large Structures]]
[[Category: MacDonald, R I.]]
[[Category: Kusunoki H]]
[[Category: Minasov, G.]]
[[Category: MacDonald RI]]
[[Category: Mondragon, A.]]
[[Category: Minasov G]]
[[Category: 3-helix coiled coil]]
[[Category: Mondragon A]]
[[Category: Alpha spectrin]]
[[Category: Alpha-helical linker region]]
[[Category: Structural protein]]
[[Category: Two repeats of spectrin]]

Latest revision as of 13:31, 13 March 2024

Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin

1u5p, resolution 2.00Å

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