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[[Image:2f73.png|left|200px]]


{{STRUCTURE_2f73|  PDB=2f73  |  SCENE=  }}
==Crystal structure of human fatty acid binding protein 1 (FABP1)==
 
<StructureSection load='2f73' size='340' side='right'caption='[[2f73]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal structure of human fatty acid binding protein 1 (FABP1)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2f73]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F73 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f73 OCA], [https://pdbe.org/2f73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f73 RCSB], [https://www.ebi.ac.uk/pdbsum/2f73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f73 ProSAT]</span></td></tr>
[[2f73]] is a 8 chain structure of [[Fatty acid-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F73 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/FABPL_HUMAN FABPL_HUMAN] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f73_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f73 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Fatty acid-binding protein|Fatty acid-binding protein]]
*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Large Structures]]
[[Category: Berg, S van den.]]
[[Category: Arrowsmith C]]
[[Category: Berglund, H.]]
[[Category: Berglund H]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Ehn, M.]]
[[Category: Ehn M]]
[[Category: Flodin, S.]]
[[Category: Flodin S]]
[[Category: Graslund, S.]]
[[Category: Graslund S]]
[[Category: Hallberg, B M.]]
[[Category: Hallberg BM]]
[[Category: Hammarstrom, M.]]
[[Category: Hammarstrom M]]
[[Category: Kotenyova, T.]]
[[Category: Holmberg Schiavone L]]
[[Category: Kursula, P.]]
[[Category: Kotenyova T]]
[[Category: Nilsson-Ehle, P.]]
[[Category: Kursula P]]
[[Category: Nordlund, P.]]
[[Category: Nilsson-Ehle P]]
[[Category: Nyman, T.]]
[[Category: Nordlund P]]
[[Category: Ogg, D.]]
[[Category: Nyman T]]
[[Category: Persson, C.]]
[[Category: Ogg D]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Persson C]]
[[Category: Sagemark, J.]]
[[Category: Sagemark J]]
[[Category: Schiavone, L Holmberg.]]
[[Category: Stenmark P]]
[[Category: Stenmark, P.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Thorsell AG]]
[[Category: Thorsell, A G.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Van den Berg S]]
[[Category: Fatty acid binding protein]]
[[Category: Lipid binding protein]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]

Latest revision as of 07:44, 23 August 2023

Crystal structure of human fatty acid binding protein 1 (FABP1)

2f73, resolution 2.50Å

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