2vk4: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2vk4.png|left|200px]]


{{STRUCTURE_2vk4|  PDB=2vk4  |  SCENE= }}
==Crystal structure of pyruvate decarboxylase from Kluyveromyces lactis==
 
<StructureSection load='2vk4' size='340' side='right'caption='[[2vk4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
===CRYSTAL STRUCTURE OF PYRUVATE DECARBOXYLASE FROM KLUYVEROMYCES LACTIS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2vk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g1i 2g1i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VK4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_16939618}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vk4 OCA], [https://pdbe.org/2vk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vk4 RCSB], [https://www.ebi.ac.uk/pdbsum/2vk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vk4 ProSAT]</span></td></tr>
[[2vk4]] is a 4 chain structure of [[Pyruvate decarboxylase]] with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g1i 2g1i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VK4 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDC1_KLULA PDC1_KLULA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vk4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vk4 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Pyruvate decarboxylase|Pyruvate decarboxylase]]
*[[Pyruvate decarboxylase|Pyruvate decarboxylase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016939618</ref><references group="xtra"/>
[[Category: Kluyveromyces lactis]]
[[Category: Kluyveromyces lactis]]
[[Category: Pyruvate decarboxylase]]
[[Category: Large Structures]]
[[Category: Konig, S.]]
[[Category: Konig S]]
[[Category: Kutter, S.]]
[[Category: Kutter S]]
[[Category: Relle, S.]]
[[Category: Relle S]]
[[Category: Weiss, M S.]]
[[Category: Weiss MS]]
[[Category: Wille, G.]]
[[Category: Wille G]]
[[Category: Asymmetric active site]]
[[Category: Decarboxylase]]
[[Category: Dimer of dimer]]
[[Category: Flavoprotein]]
[[Category: Lyase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Substrate activation]]
[[Category: Tdp]]
[[Category: Thiamine diphosphate]]
[[Category: Thiamine pyrophosphate]]
[[Category: Tpp]]

Latest revision as of 15:22, 13 December 2023

Crystal structure of pyruvate decarboxylase from Kluyveromyces lactis

2vk4, resolution 1.95Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA