1m7p: Difference between revisions

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[[Image:1m7p.png|left|200px]]


{{STRUCTURE_1m7p|  PDB=1m7p  |  SCENE=  }}
==Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog glycerol-3-phosphate (G3P).==
 
<StructureSection load='1m7p' size='340' side='right'caption='[[1m7p]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
===Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog glycerol-3-phosphate (G3P).===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1m7p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M7P FirstGlance]. <br>
{{ABSTRACT_PUBMED_12454456}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7p OCA], [https://pdbe.org/1m7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m7p RCSB], [https://www.ebi.ac.uk/pdbsum/1m7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7p ProSAT]</span></td></tr>
[[1m7p]] is a 2 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7P OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPIS_PLAFA TPIS_PLAFA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m7p ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[TIM test|TIM test]]
*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
__TOC__
 
</StructureSection>
==Reference==
[[Category: Large Structures]]
<ref group="xtra">PMID:012454456</ref><references group="xtra"/>
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Triose-phosphate isomerase]]
[[Category: Balaram H]]
[[Category: Balaram, H.]]
[[Category: Balaram P]]
[[Category: Balaram, P.]]
[[Category: Murthy MRN]]
[[Category: Murthy, M R.N.]]
[[Category: Parthasarathy S]]
[[Category: Parthasarathy, S.]]
[[Category: Beta-alpha barrel]]
[[Category: Enzyme-inhibitor complex]]
[[Category: Isomerase]]
[[Category: Tim barrle]]
Retrieved from "https://proteopedia.org/1m7p"