2vd2: Difference between revisions

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[[Image:2vd2.png|left|200px]]


{{STRUCTURE_2vd2|  PDB=2vd2  |  SCENE= }}
==The crystal structure of HisG from B. subtilis==
 
<StructureSection load='2vd2' size='340' side='right'caption='[[2vd2]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
===THE CRYSTAL STRUCTURE OF HISG FROM B. SUBTILIS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2vd2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VD2 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vd2 OCA], [https://pdbe.org/2vd2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vd2 RCSB], [https://www.ebi.ac.uk/pdbsum/2vd2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vd2 ProSAT]</span></td></tr>
[[2vd2]] is a 1 chain structure of [[ATP Phosphoribosyl Transferase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VD2 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/HIS1_BACSU HIS1_BACSU] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/2vd2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vd2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[ATP Phosphoribosyl Transferase|ATP Phosphoribosyl Transferase]]
*[[ATP phosphoribosyl transferase 3D structures|ATP phosphoribosyl transferase 3D structures]]
[[Category: ATP phosphoribosyltransferase]]
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Lapthorn, A J.]]
[[Category: Large Structures]]
[[Category: Lohkamp, B.]]
[[Category: Lapthorn AJ]]
[[Category: Riboldi-Tunniclife, A.]]
[[Category: Lohkamp B]]
[[Category: Amino-acid biosynthesis]]
[[Category: Riboldi-Tunniclife A]]
[[Category: Atp phosphoribosyl transferase]]
[[Category: Glycosyltransferase]]
[[Category: Hisg]]
[[Category: Histidine biosynthesis]]
[[Category: Transferase]]
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