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[[Image:1kra.png|left|200px]]


{{STRUCTURE_1kra|  PDB=1kra  |  SCENE=  }}
==CRYSTAL STRUCTURE OF KLEBSIELLA AEROGENES UREASE, ITS APOENZYME AND TWO ACTIVE SITE MUTANTS==
 
<StructureSection load='1kra' size='340' side='right'caption='[[1kra]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
===CRYSTAL STRUCTURE OF KLEBSIELLA AEROGENES UREASE, ITS APOENZYME AND TWO ACTIVE SITE MUTANTS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1kra]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_aerogenes Klebsiella aerogenes]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kau 3kau]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KRA FirstGlance]. <br>
{{ABSTRACT_PUBMED_8718850}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kra OCA], [https://pdbe.org/1kra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kra RCSB], [https://www.ebi.ac.uk/pdbsum/1kra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kra ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1kra]] is a 3 chain structure of [[Urease]] with sequence from [http://en.wikipedia.org/wiki/Enterobacter_aerogenes Enterobacter aerogenes]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kau 3kau]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KRA OCA].  
== Function ==
[https://www.uniprot.org/uniprot/URE3_KLEAE URE3_KLEAE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/1kra_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kra ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Urease|Urease]]
*[[Urease 3D structures|Urease 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008718850</ref><references group="xtra"/>
[[Category: Klebsiella aerogenes]]
[[Category: Enterobacter aerogenes]]
[[Category: Large Structures]]
[[Category: Urease]]
[[Category: Jabri E]]
[[Category: Jabri, E.]]
[[Category: Karplus PA]]
[[Category: Karplus, P A.]]
[[Category: Apoenzyme]]
[[Category: Nickel metalloenzyme]]

Latest revision as of 07:27, 14 February 2024

CRYSTAL STRUCTURE OF KLEBSIELLA AEROGENES UREASE, ITS APOENZYME AND TWO ACTIVE SITE MUTANTS

1kra, resolution 2.30Å

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