1jij: Difference between revisions

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[[Image:1jij.png|left|200px]]


{{STRUCTURE_1jij|  PDB=1jij  |  SCENE=  }}
==Crystal structure of S. aureus TyrRS in complex with SB-239629==
 
<StructureSection load='1jij' size='340' side='right'caption='[[1jij]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
===Crystal structure of S. aureus TyrRS in complex with SB-239629===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1jij]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JIJ FirstGlance]. <br>
{{ABSTRACT_PUBMED_11567092}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=629:[2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]-(1,3,4,5-TETRAHYDROXY-4-HYDROXYMETHYL-PIPERIDIN-2-YL)-+ACETIC+ACID'>629</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jij OCA], [https://pdbe.org/1jij PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jij RCSB], [https://www.ebi.ac.uk/pdbsum/1jij PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jij ProSAT]</span></td></tr>
[[1jij]] is a 1 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIJ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYY_STAAE SYY_STAAE] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02006]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/1jij_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jij ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:011567092</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Janson, C A.]]
[[Category: Jarvest, R L.]]
[[Category: Qiu, X.]]
[[Category: Smith, W W.]]
[[Category: Ligase]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Structure based inhibitor design]]
[[Category: Janson CA]]
[[Category: Truncation]]
[[Category: Jarvest RL]]
[[Category: Tyrosyl-trna synthetase]]
[[Category: Qiu X]]
[[Category: Smith WW]]

Latest revision as of 07:39, 7 February 2024

Crystal structure of S. aureus TyrRS in complex with SB-239629

1jij, resolution 3.20Å

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