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[[Image:1rec.png|left|200px]]


{{STRUCTURE_1rec|  PDB=1rec  |  SCENE=  }}
==THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION==
 
<StructureSection load='1rec' size='340' side='right'caption='[[1rec]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1rec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1REC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1REC FirstGlance]. <br>
{{ABSTRACT_PUBMED_8242744}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rec OCA], [https://pdbe.org/1rec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rec RCSB], [https://www.ebi.ac.uk/pdbsum/1rec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rec ProSAT]</span></td></tr>
[[1rec]] is a 1 chain structure of [[Recoverin%2C a calcium-activated myristoyl switch]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1REC OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RECO_BOVIN RECO_BOVIN] Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.<ref>PMID:8097896</ref> <ref>PMID:8392055</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/re/1rec_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rec ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Recoverin%2C a calcium-activated myristoyl switch|Recoverin%2C a calcium-activated myristoyl switch]]
*[[Recoverin%2C a calcium-activated myristoyl switch|Recoverin%2C a calcium-activated myristoyl switch]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:008242744</ref><ref group="xtra">PMID:010631973</ref><ref group="xtra">PMID:011917145</ref><ref group="xtra">PMID:012215419</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Flaherty, K M.]]
[[Category: Large Structures]]
[[Category: Mckay, D B.]]
[[Category: Flaherty KM]]
[[Category: Stryer, L.]]
[[Category: Mckay DB]]
[[Category: Zozulya, S.]]
[[Category: Stryer L]]
[[Category: Calcium-binding protein]]
[[Category: Zozulya S]]
Retrieved from "https://proteopedia.org/1rec"